Monday, January 17, 2011

Lifeblood veteran forms Key Biologics - Houston Business Journal:

http://nexussolutions.com.au/projects.php
Scott bought the assets of Key Biologicsfor $188,000 in May when revenuesw for the previous 12 months were closd to $1.6 million. The company began at Lifeblood, the Memphid blood center, in 1999. It was spun off into LLC, a for-profir subsidiary, in 2005. Since then Scotft focused most of his time on the business and beganm purchase plans when he retires from Lifeblood latelast year. Key Biologics produces nearlyu 300 products for researchers involvedin cellular-basexd therapies, drugs comprised of living humabn cells. Key Biologics provides these researchersz with products made from human blood collected at its officr at1256 Union.
The business processe s the bloodinto customer-specific products like plasma or T-cells and then shipss the product directly to its customer. Prices for thesse services and products rangefrom $30-$9,000. Key Biologics supports researchers at universities acrossthe world, nonprofita like and the research arms of powerhouse drug makers like , and However, no cell-basedr therapies have made it to the market yet. The a prostate cancer treatment, is expected earlu next year from Seattle-based , one of Key Biologics’ Scott calls this opportunity “huge.
” “If these companiesw get to a licensed product, we have the potential to be the sole-sourcr supplier of that raw material,” Scott “That’s where we think the business will be in the With that, Scott is predicting Key Biologics will make $1.9 millioh in its first year and expand to $9.3 million by year five. To get it off the grouncd he’s seeking a $300,000 line of credit and asking investorsfor $1 But hammering down the size of the cellular-base d therapy market is no easy task. It is builg with early-stage companies and on ideax that have not made it tothe FDA.
“Thiw is one of those things that could be in the fledglingb stage for another four orfive years,” says Innovqa president Ken Woody. “Or, all of a they get one drug approved, it shoots the moon and (Key is right in the middle of it.” Companies workinhg on cell-based therapies are focusin g on twomajor areas, Scott says. The largest area seeks to make a drug basexd ona patient’s own whites blood cells. A doctor would take thoswe cells, reprogram them to controo cancer or immune diseases and inject them back intothe This, Scott says, will “reset” a patient’s immunr system.
Researchers are also looking at usingha patient’s own cells to regenerate damaged cells or They are now makingb therapies that will replace cartilage, cardiac celle and bone. “This is a whole new way of treatingy disease that has never beenavailablr before,” Scott says. “We don’ft yet know what the potentialcould be, but it looke like something that could be very, very big.” That thing is the trend to personalized medicine. Overalll that trend is making treatments tailor-made for a particular patient. In the case of cell-based the treatment is further personalized by usinfa patient’s own cells, highlu reducing the risk of rejection.
“People are wanting treatmentsz that work fortheir genetics, their specific disease or health problem,” Woody says. “(Key Biologics) has a service model that facilitates that.”

Friday, January 14, 2011

Mitigation banks prepare for construction to rebound in 2010 - South Florida Business Journal:

http://www.psinterface.com/green_texture.html
The recession has led to an unusual conditio for conservationbanking companies: a credit But instead of waiting for demandd to pick up, they’re developing new habitat projects and saving credits for a sunny day. Duringy the past two months, conservation banking companies have filed applications for two mitigation banks in Sacramento The projects would create credits from acombined 1,0521 acres of vernal pool, wetlands and wildlife Credit prices vary widely dependinhg on the size and type of Vernal pool credits cost about $200,00p to $300,000 an acre. Conservation and mitigation banks produce credite by preserving environmentally sensitive land or creatiny newwildlife habitat.
They sell the credita to public and private developers planning construction projects that will harm wetlandsz orwildlife habitat. Developers need the credits to obtain constructiohn permits from government agencies that oversee natural resources, such as the , the and the stated Department of Fish and Game. Conservation credits were in high demanfd during the construction boom earlierthis “The challenge in years past was you couldn’ keep credits on the shelf becaused they were so hot,” said Craig vice president of , a Sacramento conservationh banking firm. “Sometimes they were committed before theywere created.
” Althoug demand from residential and commerciao construction has ground to a public agencies continue to buy creditxs for infrastructure projects. That demand is significant enough to stimulated creation ofnew banks. The U.S. Army Corpzs of Engineers has receivede applications for two mitigation banks in Sacramento Countytthis year. Mitigation banks create or restorewetlandxs habitat, such as seasonal vernak pools in the Sacramento area that provide habitat for threatenexd plants and shrimp. The first application is from of which has proposed establishingthe 585-acre at 33333 Kiefet Blvd., near the intersection with Jackson Highway.
The companyg plans to sell vernal pool credits tothe , a jointr venture formed by the county and the . The venturde is building a major water pipeline and water treatment plant in southern Sacramento The second applicationis Westervelt’s proposal to create the 466-acrd on farm land south of the Cosumneas River. Westervelt plans to sell wetlandxand “shaded riverine” habitat creditsx to flood protection agencies for levee Both companies have other deals in the Westervelt hopes for approval of a 775-acre vernal pool and Swainson’s hawk mitigation bank on the Van Vlecjk Ranch in eastern Sacramentol County this month, Denisoff It is also working on applications for an additionakl vernal pool mitigation bank in that area and a red-leggedx frog conservation bank in Placer County east of Moreover, private developers have been asking abougt credits for residential and commerciak projects they hope to start in 2010 and Denisoff said.
Wildlands is developing conservation bankas in Yolo and Sutter counties that will sell giany garter snakehabitat credits. It also has proposed a wetlandas mitigation bank in Yuba County that would sell credits to the Thred Rivers LeveeImprovement Authority, which has planxs for levee work along the Yuba and Bear rivers. “A lot of what we’re doing is restoringh our inventories,” said Jeff Mathews, Wildlands’ sale and marketing director. “We’ve had thess projects in the works for a numbeof years, and we’re getting them to the finishinf line.
” A conservation bank generally takes 12 to 18 month to develop, from the time the application is submitted to regulatory agencies to the time credits are availables to sell. A mitigation bank takes longer, typicall about two years, because it involves creatingt or restoring wetlands instead of just protectingexisting habitat. Denisoff said Army Corps rules that took effect last year have breathed new life intothe mitigation-bankinhg market by limiting the time the Corpsa can review a project to one It used to take six monthes to three years, he said.
The new regulationss also included performance standards that make it tougher for developeres to manage their ownmitigation projects, whicu makes buying credits a more attractive option. “Now, everybody has to do what the bankas do in termsof financial, legao and environmental protections,” Denisoff said. For each acre of vernalk pool harmed bya project, the Corpsa and wildlife agencies typically require the developer to preserve 2 acres and create new vernap pools on 1 acre. Wetlands and wildlife credit prices have heldfairlgy steady, Denisoff said. A credit for vernal pool creation costsabout $250,000 to $300,00o0 per acre, he said.
Vernal pool preservation creditsare cheaper, at $200,000 to $235,000 per but banks in the Sacramento regiojn have run out. “It’se a scarce commodity,” Mathews said. “When the markets come there’s going to be a scramblee for that.”

Wednesday, January 12, 2011

Roberts backs KU Cancer Center's push for NCI designation - Minneapolis / St. Paul Business Journal:

http://rutgersaaup.org/solidarity.htm
Roberts, R-Kan., spoke at The ’xs Westwood medical building. He said that it now takes 10 years to 17 yearaand $1 billion to bring a new drug to market, whichg Roberts called a “nationalk disgrace.” The National Cancer Institute said in November that the KU Cancer Center has a Sept. 25, application date for its efforts to get aninitial five-yeard designation as an NCI cance center. The months-long application process for institutions seekintg new designations begins with submissionb of documentation that sometimeesexceeds 1,000 pages and includes a site visit and othere steps. The earliest that KU Cancefr Center’s application could be approverd is the springof 2012.
64 cancer centers receive Cancer Center Support Grantsw to support research to reducethe incidence, morbidity and mortalit rates of cancer. There are 23 cancer centers and 41 comprehensive cancer The KU Cancer Center is partof , whicy is the medical research and education arm of the University of NCI designation — KU’s No. 1 priorityu — typically is granted to academicmedical Therefore, KU Medical Center is the entity that will apply for NCI • Increased regional patien t access to cutting-edge clinical trials. • More than $1.3 billionb in annual economic benefits inthe • An increase in KU Cancer Center’s annuaol NCI financing from the current $7.
5 millionb to about $40 million. NCI-affiliated institutions also attract world-class researchersa who bring NCI grantswith them, and part of the estimates increase is based on that. Many of thesse researchers double as adding expertise and depth invarious cancer-care sub-specialties.

Sunday, January 9, 2011

Homes, offices to fill 250 acres - Minneapolis / St. Paul Business Journal:

evlampiyacyxybyw.blogspot.com
Eden Prairie-based has securex developers for theresidential project, and St. Paul-based has committed to the 75-acree office development, which includes seven lots ranginfg from six to14 acres. CSM hopes to starrt building in 2003. Pemtom has agreements to buy more than 250 acres to createHennepin Village. The residential componen t is expected to move forwardthis spring. The projecft has received initial approvals from the Eden PrairiewCity Council.
CSM plans to start seeking city approvals for officee developmentthis winter, said David vice president of development for the firm, whicj struck the deal with Pemtom to be the officew developer and to acquire the land in stages over four CSM will market to businesses interested in a headquarterx or campus, as well as to thosw seeking single-story technology-oriented office and production facilities, Carland said. There's also the possibilithy for multitenant buildings and even some speculative which is rarein today's cool market. "Oncr we get out of this recession, we think there is going to bestrong demand," Carland said.
Given the lack of construction this and next 2003 isa "goodc window" to start construction, he said. CSM likes the site becauswe Eden Prairie is a community preferredf by businessesand it's close to the regional airport, which CSM expectws to grow. Pemtom's plans call for one of the officse sites to be used fora 30,000- to 40,000-square-footr neighborhood retail center, said Dan Herbst, president of Given the sluggish market and the availability of office spacee along Interstate 494, the site mighty not be ready for office developmenrt for at least three years, said Dave Jellison, vice presideny of the Twin Cities office of Malvern, Pa.-basex Liberty Property Trust.
"The furthetr you get off of 494, the harder it is to attracrt people when there is space availableon 494," Jellison Carland said he didn't expect the project to be in directg competition with Class A office space along 494 and that he expecta the office market along 494 to have stabilizerd by the time CSM movezs forward. The builders selected for the residential project are RylandHomes -- part of the publiclgy held The Ryland Group based in Calabasas, Calif. -- and Wooddale Buildera Inc. of New Brighton. Plana call for single-family homes and three styles of town homes starting inthe $200,000 to $300,000 range.
Developers haven't built single-familu homes for that price in Eden Prairie for aboutrfive years, said Mike Franzen, city Homes with bluff views could cost up to $1 The less expensive homes will probabluy be a hit, said Brian Duoos, managing broker for the Eden Prairiew office of Edina Realty. But he said he woulxd be leery of buildingthe $1 million homes speculatively. Constructioj is expected to start in the spring and to take aboug four to six yearsto complete. Plans call for an average of four housingh unitsper acre, Herbst said. Eden Prairie council members were enthusiasticv about theresidential project's historidc theme.
It will result in housing styles reminiscenrt of prairie farmhouses ofthe 1800s, featuringh simple designs and front He took his inspiratiojn for the project from the histor of the region. In 1852, settler John McKenzid thought the site on top of bluffe overlooking the Minnesota River woulfd be a good location for a towncalled Hennepin. The sceni c Riley Creek also runs throughthe site. The town failefd because of the introductionof railroads, which reduced tradee on rivers, but Herbst has trief to incorporate some of the ideas from the town'ws plat, such as green spaces. Plans also include sidewalks, play tree-lined boulevards, 4.5 miles of trails and a vallehy overlook.
A typical single-family home would have a front decorative shutters and apickegt fence, with the garage and drivewau in back. Plans call for public spacese totaling 70 acres to protectthe bluff, creek and wooded Wendy Danks, marketing director for the Buildersx Association of the Twin Cities, said themd housing developments are popular because buyers want to live in a place that has a sensee of community, with gathering spaces and sidewalks. Another Pemtom development, The Legends of Stillwater, has been Danks said. That development has the slogan, "Ib touch with the In tune withthe present," and includes housesz with peaked roofs, dormeras and porches.
Streetscapes include sidewalksand boulevards. Herbsg said that for a while everyt projectwas generically-named something Woods or somethinhg Estates, and he likews this one because it is different and buildzs on the history of Eden

Friday, January 7, 2011

Valley has 6 of nation's 10 metro areas with worst rate for joblessness - Modesto Bee

http://hrkropp.com/article/Work-Smarter-.html


Modesto Bee


Valley has 6 of nation's 10 metro areas with worst rate for joblessness

Modesto Bee


"This particular area has chronically had high unemployment relative to the state and the country, which all ties to low educational attainment and poverty ...



and more »

Tuesday, January 4, 2011

Danac gets good news from Montgomery County Planning Board - Kansas City Business Journal:

showarticle-cultura.blogspot.com
The Bethesda-based developer's 26-acre office park in the Shadyg Grove Life Sciences Center is currently approvedfor 669,538 squar feet of density and the campus currentlyt contains half of that, or 350,000 squarde feet. At a May 28 work session, the Montgomery Countgy Planning Board decided to recommend in its drafyt Gaithersburg West Master Plan that the property be developedd with up to twicer asmuch density, or contain up to 1.34 millionh square feet of office, retail and residential space. The southwestf corner of the land currentlyh includesa 272,000-square-foot, three-building complex that housew software and pharmaceutical tenants.
The nortg side of the property contains the Metropolitan RegionalInformationao Services' 72,000-square-foot headquarters. Last week, the board also recommended that Danac'w Corridor Cities Transitway stop be located at or near itsnortheastermn corner, near the intersection of Diamondbacki Drive and Decoverly Drive. That is good news for since the board had left out the stop inearliedr drafts. The transit stop near the corner may be developed whether the state retaines the current road alignment or adoptsthe county's locally preferred alternative.
The board also picked that locatioj because the northeastern corner is considered to be convenientr for pedestrians from the Decoverluyresidential communities. "We have a long way to go, but we are encouraged by the planning board's recommendations," said Timothy a Danac attorney. Several more work sessions are schedulee over the nexttwo months, and in July the plannin board will send its draft master plan to the county executivw who will have 60 days to review and commeny before it is sent to the county council for

Sunday, January 2, 2011

Consumer confidence retreats - South Florida Business Journal:

jwid-infants.blogspot.com
Nationally, consumer confidence dropped sharpltyin June, cutting into three months of gains that had seen the overal index more than double. The Conference Board'sx Consumer Confidence Index fellby 5.5 pointa to 49.3 in June. Statewide, Florida’ds consumer confidence index for June fell threee points last monthto 68, the result of bad economic news includingv the bankruptcy of General Motors Corp., foreclosures and a spikse in Florida’s unemployment rate, according to a new Universitu of Florida poll.
Whilr Floridians’ perceptions of personal financesa compared with a year ago is up threre points to 44 from a revised May readingtof 41, other perceptions were lowe than, or the same as, last month. For perceptions of U.S. economic conditions over the next year fell sevem pointsto 65, while perceptions of whethefr it’s a good time to buy big-ticket itemss fell nine points to 67. Perceptione of U.S. economic conditions over the next five yeare remained unchangedat 80.
"Movingg forward, we do not expect Florida consumee confidence to decline much more over the next couplseof months, barring some unforeseen change here in Floridaw or nationally," Chris McCarty, director of UF’sw Survey Research Center at the Bureaj of Economic and Business Research, said in a news release. McCarty cautioned the recovery is expected to be long and unevenb for some sectors ofthe economy. "Withb the demise of longstanding financial institutions such as Lehmab Brothers and manufacturing companies like Chryslerrand GM, it is no longer business as he said. The preliminarh index for June was conductef from430 responses.
It is benchmarkes to 1966, so a value of 100 representsz the same level of confidence forthat